STEVISSE advanced botanical ingredient




Obtained by subcritical water extraction of Organic Stevia leaves, STEVISSETM is highly concentrated in actives (chlorogenic acids), whose biological effects are similar to retinol



In vitro tests:

Very high free-radical scavenging activity: ORAC value 12 000 µmol TE/100 g
Stimulation of a subset of genes (HMOX-1, OSGIN-1 et TXRND-1) involved in the cellular antioxidant and anti-inflammatory defence in human dermal fibroblasts
Inhibition of the expression of matrix metalloproteinases (MMPs) genes in human dermal keratinocytes (MMP-1 and MMP-3)
Inhibition of several keratinocyte differentiation markers (IVL, CALML5)

In vivo tests:

Increase of 58% of the radiance and 53% of the luminosity of the complexion after 28 days (clinical scoring)
Decrease of 17% of the surface, 19% of the lenght and 11% of the depth of wrinkles (crow's feet)



Innovative and exclusive in France, the organic Stevia culture initiated in 2012 by OVIATIS and INRA is now fully integrated into the sustainable development model. OVIATIS, a transformation and trading company located in Agen has created a collection of numerous Stevia genotypes with very different characteristics. One of them was selected by PHENOBIO for its high polyphenol content and its strong antioxidant property.


  • Reduces wrinkles and fine lines
  • Protects skin cells from oxidative aging
  • Creates an even skin tone



Skin care for face, body, "décolleté", hands, 1.0 - 2.0%



Nom INCI: Stevia rebaudiana leaf/stem extract (and) Glycerin (and) Water

China Compliant



*Référentiel définissant les Produits Cosmétiques Ecologiques et Biologiques disponible sur